Stumbled upon this noteworthy piece from Dr Christianson. It’s called Top 10 Myths About Natural Desiccated Thyroid.
It offers us some fascinating ideas. This one was particularly thought-provoking:
it is better to take T3 once daily because thyroid hormones abide by a circadian rhythm. Your body releases the bulk of them during the late evening/early morning. So taking NDT before bed or early in the morning actually achieves what would be happening if your thyroid was operating normally.
Give the rest of this remarkably detailed article from Dr Christianson for more information and context.